About the Feldheim Laboratory

The Feldheim lab is interested in how the mammalian visual system develops.  Light is detected by the photoreceptors in the retina and processed into 20 channels of information that is sent to the brain.  These channels are formed by creating unique circuits within the retina, with the output of these circuits being the retinal ganglion cells (RGCs).  Some RGCs fire action potentials in response to increases in luminance while others respond preferentially by motion.  Different brain areas receive information from specific subsets of RGCs, and lead to the execution of specific visually evoked behaviors. One overall goal of our lab to understand how retinal circuitry is formed during development and how each RGC type contributes to perception and behavior. A second goal is to understand how the brain integrates information within the visual system and between sensory areas using the superior colliculus as our model.  We have close collaborations with Alexander Sher and Alan Litke’s labs.  Together we are integrating molecular genetic, anatomy and physiological recording techniques to study these processes.